literature_article

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Accelerated Head and Body Growth in Infants Later Diagnosed With Autism Spectrum Disorders: A Comparative Study of Optimal Outcome Children
Potentially, here is some very helpful information for parents and physicians to help evaluate possible outcomes earler rather than later in a patient’s life.
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Factors Associated with GI Symptoms in Autism Spectrum Disorders (ASD)
After the AAP’s “traditional” approach to this problem (i.e. constantly challenging the association of GI symptoms in ASD), this is a step in the right direction.
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Gastrointestinal Disorders in Individuals With Autism Spectrum Disorders
OK, so why is this headline “Evidence lacking for special diets for treating ASDs” showing up in much of the mainstream media? Because the supplement and reports represent the Academy of Pediatrics, who must be so afraid of offending conventional pediatricians that they would rather NOT recommend a benign and fairly simple dietary intervention for fear of … what?? ? That there may be other treatments which could prove of value? That maybe they should have been more vigilant and proactive about this epidemic? Boy, they sure got on the H1N1 Express without corroborating research in reputable journals consisting of peer-reviewed blinded, randomized stepwise trials not to mention all of the other questionable vaccination schedules that they have foisted upon our unsuspecting public. So now, although the committee has just discovered that at-risk non-verbal populations may suffer with undetected gastrointestinal discomfort, there isn’t enough evidence to warrant something as risky and expensive as recommending a healthy diet. Anyway, the ASD community can, at least, point to the title as some proof that the AAP cannot totally ignore the epidemic, no matter how hard they have tried.
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Randomized, Controlled Trial of an Intervention for Toddlers With Autism: The Early Start Denver Model
It’s great to know that “mainstream” research is finally looking at this epidemic, and documenting treatment. Now, if the insurance companies would get on board…
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Safety and Efficacy of Oral DMSA Therapy for Children with Autism Spectrum Disorders: Parts A and B
OK, here are two peer-reviewed journal articles, for the “real” doctors who only use “safe” medications that are not off-label and have been thoroughly reviewed.
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Medication and Parent Training in Children With Pervasive Developmental Disorders and Serious Behavior Problems: Results From a Randomized Clinical Trial.
Well, they used Risperidone and Risperidone PLUS parent-trained behavioral management and, guess what? Of course, behavioral therapy plus medication improved the child’s symptoms! Watch out now, “traditional” docs will use this study to prove that the children need meds.

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Incidence of Gastrointestinal Symptoms in Children With Autism: A Population-Based Study
Lemme get this straight, “Significant differences between autism case and control subjects were identified” but “No significant associations were found between autism case status and overall incidence of gastrointestinal symptoms” because autistic children tend to drink less fluids and they are picky eaters. Are you guys at Mayo kidding? This totally specious conclusion was broadcast all over the mainstream media, making the physicians who care for autism and their parents look like kooks. “Research” such as this is the reason why the autism community has little faith in traditional medicine.
bullet Antidepressant No Help for Autism Behaviors
This well-done research shows the power of placebo effect, even in our patients. Parents can see that the drug, which is very potent, showed LESS improvement than a sugar pill, with MANY more side effects!
bullet Hyperbaric treatment for children with autism: a multicenter, randomized, double-blind, controlled trial
Dr. Rossignol and others have done a great job trying to demonstrate efficacy of this controversial and somewhat expensive treatment option. Still to be determined are the expectation of timing and duration of improvement as the authors have noted in their discussion.
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Randomized trial of hyperbaric oxygen therapy for children with autism
One of the lead authors, Dr. Bradstreet, is a partner in Dr. Rossignol’s practice (article cited above). Which one should we believe? Obviously, the jury is still out. Unfortunately, this leaves a parent without good evidence for undertaking such a resouce-intensive intervention. Forty treatments of HBOT would cover ~100 hours of ABA, which HAS been demonstrated as leading to significant improvement in behavior. Also, one needs to question why BOTH groups in this study improved – possibly related to the improvement that takes place anyway over time. Furthermore, these two studies used 1.3 ATM and 24% oxygen, begging the question about the outcome when 1.5 ATM and 100% oxygen are employed (typcial “hard” dive chambers). Well, at least the “real” scientific community can’t complain that alternative medicine is not scrutinizing various therapies.
bullet Positive Association Between Attention-Deficit/ Hyperactivity Disorder Medication Use and Academic Achievement During Elementary School
Academically, the medicated children did a little better, but not as well as non-ADHD students. The authors point out the need for more long-term studies on medicated patients.
bullet Amydala Enlarged in Young Autistic Children
And what would be the cause of this enlargement… inflammation, perhaps?
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Global methylation profiling of lymphoblastoid cell lines reveals epigenetic contributions to autistic spectrum disorders and a novel autism candidate gene, RORA, whose protein product is reduced in autistic brains.
More evidence of a genetic predisposition
bullet Prevalence of Parent-Reported Diagnosis of Autism Spectrum Disorder Among Children in the US, 2007
The documented increase is NOT ONLY due to a broader diagnosis or due to increased awareness and improved screening. The 400 pound gorilla in the report was the question of WHY and WHAT ABOUT our polluted food and water, and oh, yes, the new vaccination protocols.
bullet Absence of preferential looking to the eyes of approaching adults predicts level of social disability in 2-year-old toddlers with autism spectrum disorder.
Yep, it CAN be diagnosed earlier! Let’s hope the pediatricians and child neurologists see this one.